Cancer, its Risk Factors and Remedy

                                                                                Cancer, its Risk Factors and Remedy

Cancer is a disease in which some of the body’s cells grow uncontrollably and spread to other parts of the body. Cancer can start almost anywhere in the human body, which is made up of trillions of cells. Normally, human cells grow and multiply (through a process called cell division) to form new cells as the body needs them. When cells grow old or become damaged, they die, and new cells take their place. Sometimes this orderly process breaks down, and abnormal or damaged cells grow and multiply when they shouldn’t. These cells may form tumors, which are lumps of tissue. 

Cancer Risk Factors

A risk factor is anything that may increase a person's chance of developing a disease. A risk factor does not necessarily cause the disease, but it may make the body less resistant to it. The following risk factors and mechanisms have been proposed as contributing to cancer:

• Lifestyle factors. Smoking, a high-fat diet, and working with toxic chemicals are examples of lifestyle choices that may be risk factors for some adult cancers. Most children with cancer, however, are too young to have been exposed to these lifestyle factors for any extended time.

• Family history, inheritance, and genetics may play an important role in some childhood cancers. It is possible for cancer of varying forms to be present more than once in a family. It is unknown in these circumstances if the disease is caused by a genetic mutation, exposure to chemicals near a family's residence, a combination of these factors, or simply coincidence.

• Some genetic disorders. For example, Wiskott-Aldrich and Beckwith-Wiedemann syndrome are known to alter the immune system. The immune system is a complex system that functions to protect our bodies from infection and disease. The bone marrow produces cells that later mature and function as part of the immune system. One theory suggests that the cells in the bone marrow, the stem cells, become damaged or defective, so when they reproduce to make more cells, they make abnormal cells or cancer cells. The cause of the defect in the stem cells could be related to an inherited genetic defect or exposure to a virus or toxin.

• Exposures to certain viruses. Epstein-Barr virus and HIV, the virus that causes AIDS, have been linked to an increased risk of developing certain childhood cancers, such as Hodgkin and non-Hodgkin lymphoma. Possibly, the virus alters a cell in some way. That cell then reproduces an altered cell and, eventually, these alterations become a cancer cell that reproduces more cancer cells.

• Environmental exposures. Pesticides, fertilizers, and power lines have been researched for a direct link to childhood cancers. There has been evidence of cancer occurring among nonrelated children in certain neighborhoods and/or cities. Whether prenatal or infant exposure to these agents causes cancer, or whether it is a coincidence, is unknown.

• Some forms of high-dose chemotherapy and radiation. In some cases, children who have been exposed to these agents may develop a second malignancy later in life. These strong anticancer agents can alter cells and/or the immune system. A second malignancy is a cancer that appears as a result from treatment of a different cancer.

Cancer Remedy options include:

• Surgery. The goal of surgery is to remove the cancer or as much of the cancer as possible.

• Chemotherapy. Chemotherapy uses drugs to kill cancer cells.

• Radiation therapy. Radiation therapy uses high-powered energy beams, such as X-rays or protons, to kill cancer cells. Radiation treatment can come from a machine outside your body (external beam radiation), or it can be placed inside your body (brachytherapy).

• Bone marrow transplant. Your bone marrow is the material inside your bones that makes blood cells from blood stem cells. A bone marrow transplant, also knowns as a stem cell transplant, can use your own bone marrow stem cells or those from a donor.

• A bone marrow transplant allows your doctor to use higher doses of chemotherapy to treat your cancer. It may also be used to replace diseased bone marrow.

• Immunotherapy. Immunotherapy, also known as biological therapy, uses your body's immune system to fight cancer. Cancer can survive unchecked in your body because your immune system doesn't recognize it as an intruder. Immunotherapy can help your immune system "see" the cancer and attack it.
• Hormone therapy. Some types of cancer are fueled by your body's hormones. Examples include breast cancer and prostate cancer. Removing those hormones from the body or blocking their effects may cause the cancer cells to stop growing.
• Targeted drug therapy. Targeted drug treatment focuses on specific abnormalities within cancer cells that allow them to survive.

• Cryoablation. This treatment kills cancer cells with cold. During cryoablation, a thin, wandlike needle (cryoprobe) is inserted through your skin and directly into the cancerous tumor. A gas is pumped into the cryoprobe in order to freeze the tissue. Then the tissue is allowed to thaw. The freezing and thawing process is repeated several times during the same treatment session in order to kill the cancer cells.

• Radiofrequency ablation. This treatment uses electrical energy to heat cancer cells, causing them to die. During radiofrequency ablation, a doctor guides a thin needle through the skin or through an incision and into the cancer tissue. High-frequency energy passes through the needle and causes the surrounding tissue to heat up, killing the nearby cells.

• Clinical trials. Clinical trials are studies to investigate new ways of treating cancer. Thousands of cancer clinical trials are underway.

Sources: cancer.gov, stanfordhealthcare.org and mayoclinic.org